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Type: Topical anesthetic (numbing cream)
Main ingredient: Lidocaine 10.56%
Purpose: Temporarily numbs the skin to reduce pain during cosmetic or medical procedures.
High strength: 10.56% lidocaine for strong numbing effect.
Fast acting: Usually begins numbing within 5–15 minutes.
Long lasting: Numbing effect can last 60–90 minutes.
Deep penetration: Can numb skin up to about 8 mm depth depending on application.
Professional use: Often used in clinics and aesthetic salons.
H-Lido is used to reduce pain during:
Tattoo procedures
Permanent makeup (PMU) / Microblading
Laser treatments
Microneedling
Mesotherapy
Chemical peels
Hair removal / waxing
Minor dermatology procedures
Clean the treatment area.
Apply a thick layer of cream.
Cover with plastic wrap (occlusion) to enhance absorption.
Wait 20–30 minutes before the procedure.
Remove cream and disinfect skin.
For external use only.
Do not apply to broken skin or large areas without medical guidance.
Possible side effects include irritation, redness, dizziness, or allergic reactions.
H-Lido is commonly used before:
Tattoo sessions
Permanent makeup
Microblading
Laser therapy
Mole removal
Wart removal
Freckle removal
Microneedling
Mesotherapy
Chemical peels
Skin rejuvenation
Biorevitalization
Hair removal
These treatments involve needles, lasers, or abrasions where numbing helps patient comfort.
Typical clinical protocol:
Clean and disinfect treatment area.
Apply thick layer (0.25–0.66 g) of cream.
Cover with plastic wrap (occlusion).
Wait 20–30 minutes.
Remove cream and disinfect skin before procedure.
Occlusion improves penetration and effectiveness.
Recommended safety guidelines:
Do not exceed 2 g per day of high-strength lidocaine cream.
Avoid applying on:
broken skin
infected areas
large body areas
Contraindications
Allergy to lidocaine
Hypersensitivity to amide anesthetics
Severe skin inflammation
Most users experience no serious problems, but possible reactions include:
Redness
Skin irritation
Mild burning
Temporary swelling
Allergic reaction (rare)
Stop using if irritation persists.
Store at 1–30°C
Keep container sealed
Protect from direct sunlight
Shelf life typically 36 months from manufacture date.
Benefits of 10.56% creams:
Stronger than standard 4–5% lidocaine creams
Faster and deeper numbing
Long-lasting effect
More comfortable aesthetic procedures for patients
Local anesthetic belonging to the amide anesthetic group
Blocks sodium channels in nerve endings
Stops pain signals traveling to the brain
This temporarily numbs the skin in the treatment area.
Penetrates skin up to ~8 mm depth depending on thickness of application.
Typical formula for H-Lido / SM-Lido 10.56% creams:
Active ingredient
Lidocaine – 105.6 mg (10.56%)
Other ingredients
Methylparaben (preservative)
Isopropyl Myristate
Stearyl Alcohol
Propylene Glycol
Carbomer 940
Trolamine
Polysorbate 60
Purified Water
These ingredients stabilize the cream and improve skin absorption and texture.
Starts working in 5–15 minutes
Maximum numbing in 20–30 minutes
Numbing effect lasts 60–90 minutes after application.
Can numb deeper dermal layers for procedures such as tattooing or microneedling.
High-strength lidocaine creams can penetrate approximately:
| Skin Layer | Depth |
|---|---|
| Epidermis | ~0.1 mm |
| Dermis | 1–2 mm |
| Maximum anesthetic reach | up to 6–8 mm |
Penetration improves when:
thicker layer applied
occlusion used
longer waiting time allowed
H-Lido is widely used in medical aesthetic procedures.
Tattooing
Tattoo touch-ups
Tattoo removal (laser)
Microblading
Eyebrow tattoo
Lip blush
Eyeliner tattoo
Laser resurfacing
Wart removal
Mole removal
Skin biopsies
Microneedling
Mesotherapy
PRP injections
Dermal filler injections
Botox injections
Chemical peels
Clean area with antiseptic
Dry the skin completely
Apply 1–2 mm thick layer.
Cover with:
plastic wrap
occlusive film
This:
prevents evaporation
increases penetration
improves numbing strength
Allow 20–30 minutes.
Remove wrap
wipe cream
disinfect skin again
Procedure can then begin.
Recommended safe limits vary by manufacturer.
Typical dermatology guideline:
| Application Area | Maximum Amount |
|---|---|
| Small procedure area | 1–2 g |
| Medium area | 2–5 g |
| Large area | clinical supervision required |
Avoid applying large quantities on:
broken skin
inflamed skin
large body surfaces.
The anesthetic effect depends on:
lidocaine concentration
exposure time
occlusion use
Typical duration:
| Strength | Duration |
|---|---|
| 5% Lidocaine | 30–60 minutes |
| 10.56% Lidocaine | 60–90 minutes |
Some patients may experience numbness for up to 2 hours.
Lidocaine topical anesthetics are generally safe when used properly.
redness
mild swelling
itching
tingling sensation
dizziness
allergic reaction
rash
methemoglobinemia (extremely rare)
Extra caution for:
children
elderly
patients with liver disease
lidocaine allergy
Do NOT use if patient has:
hypersensitivity to lidocaine
allergy to amide anesthetics
severe skin infection
open wounds
severe dermatitis
Proper storage ensures stability:
Temperature: 1°C – 30°C
Avoid:
heat
freezing
direct sunlight
Shelf life typically 3 years (36 months).
| Brand | Lidocaine Strength | Typical Use |
|---|---|---|
| EMLA | 2.5% lidocaine + prilocaine | medical procedures |
| TKTX | 40% mix anesthetics | tattoo numbing |
| H-Lido | 10.56% lidocaine | aesthetic clinics |
| Beyond Numb | strong lidocaine formula | tattoo & PMU |




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